Description

Prostaglandin F2 Ethyl Ester is a chemically modified, esterified derivative of the naturally occurring prostaglandin F2α (PGF2α). This modification enhances its stability and lipophilicity, making it a crucial intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in the fields of reproductive health, ophthalmology, and inflammation.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of prostaglandin-based drugs targeting ocular pressure (glaucoma), fertility management, and inflammatory pathways.
• Biochemical Research: Used as a reference standard and active compound in cell-based assays and pharmacological studies to investigate prostaglandin receptor (FP receptor) activity and signaling mechanisms.
• Veterinary Medicine: Employed in the development of treatments for animal reproductive cycle management, such as estrus synchronization in livestock.
• Cosmeceutical R&D: Investigated for potential applications in formulations targeting skin renewal and hair growth stimulation due to its cell-proliferative properties.
• Process Development: Serves as a critical standard for quality control and analytical method development (e.g., HPLC, GC) during the scale-up of prostaglandin analog manufacturing.

Basic Information

Product Name	Prostaglandin F2 Ethyl Ester
CAS No.	53764-89-9
Molecular Formula	C₂₂H₃₈O₅
Molecular Weight	382.54 g/mol
Synonyms	PGF2α Ethyl Ester; Ethyl (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oate; Dinoprost Ethyl Ester; Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, ethyl ester, (5Z,9α,11α,13E,15S)-; Ethyl 9,11,15-trihydroxyprosta-5,13-dien-1-oate
EINECS	Contact for details

Quality Control

Our Prostaglandin F2 Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development use. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.