Description

Cytochalasin H is a potent secondary metabolite belonging to the cytochalasin family, known for its specific biological activity as an inhibitor of actin polymerization. This compound is a critical research tool in cell biology and pharmacology for studying cytoskeletal dynamics, cell motility, and membrane trafficking processes. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in fundamental life science research and drug discovery programs.

Application

• Cytoskeleton Research: A fundamental tool for disrupting actin filament networks to study cell shape, division, and intracellular transport mechanisms.
• Cell Biology Studies: Used to investigate processes such as endocytosis, exocytosis, and cell migration by selectively inhibiting actin-dependent functions.
• Pharmacological Screening: Serves as a reference compound or positive control in assays designed to discover novel compounds targeting the cytoskeleton.
• Toxicology Research: Employed to understand the mechanisms of mycotoxins and to study cellular responses to cytoskeletal disruption.
• Developmental Biology: Applied in model organism studies to examine the role of actin in embryonic development and tissue morphogenesis.

Basic Information

Item	Detail
Product Name	Cytochalasin H
CAS No.	53760-19-3
Molecular Formula	C₂₉H₃₇NO₆
Molecular Weight	507.61 g/mol
Synonyms	Cytochalasin H; NSC 339524; 22,23-Dihydro-7,20-dihydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13,21-triene-1,23-dione; [14]Cytochalasin H; 7,20-Dihydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13,21-triene-1,23-dione, 22,23-dihydro-; Phomin; Deacetylphomin
EINECS	Contact for details

Quality Control

Our Cytochalasin H is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant quality standards for research chemicals, ensuring reliable performance in your experimental systems.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.