Description

n-Acetyl-N'-Nitrosotryptophan Methyl Ester is a specialized nitrosated tryptophan derivative of significant interest in biochemical and pharmaceutical research. This compound matters as a critical intermediate and model compound for studying nitrosation processes, protein modifications, and related biochemical pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and advanced chemical synthesis laboratories focusing on amino acid chemistry, carcinogenesis studies, and the development of analytical standards.

Application

• Biochemical Research Intermediate: Serves as a key synthetic precursor in the study of nitrosamine formation and tryptophan metabolism.
• Pharmaceutical R&D: Used in the investigation of protein modifications and the development of targeted therapeutic agents.
• Analytical Standard: Employed as a high-purity reference standard in chromatography (HPLC, LC-MS) for method development and quality control in analytical laboratories.
• Carcinogenesis Studies: Acts as a model compound in research focused on the mechanisms of nitroso-compound induced mutagenesis and carcinogenicity.
• Academic Research: Utilized in universities and research institutes for advanced studies in organic synthesis, bioorganic chemistry, and toxicology.
• Specialty Chemical Synthesis: Functions as a building block for the synthesis of more complex, nitrosated molecules for various investigative purposes.

Basic Information

Product Name	n-Acetyl-N'-Nitrosotryptophan Methyl Ester
CAS No.	53659-33-9
Molecular Formula	C14H15N3O4
Molecular Weight	289.29 g/mol
Synonyms	N-Acetyl-N'-nitrosotryptophan methyl ester; Methyl N-acetyl-N'-nitrosotryptophanate; N'-Nitroso-N-acetyltryptophan methyl ester; L-Tryptophan, N-acetyl-N'-nitroso-, methyl ester; Ac-NNO-Trp-OMe; 2-Acetamido-3-(1-nitroso-1H-indol-3-yl)propanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our n-Acetyl-N'-Nitrosotryptophan Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, IR) for structural confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and support your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystals
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.