Description

11-Deoxy-16,16-Dimethyl Prostaglandin E2 is a synthetic prostaglandin analog, a key intermediate and research tool in advanced pharmaceutical development. This compound is valued for its structural specificity, enabling targeted research into prostaglandin-mediated biological pathways and therapeutic applications. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel prostaglandin-based therapeutics and as a reference standard in bioactivity studies.
• Biochemical Research: Used as a tool compound to investigate the role of prostaglandins in cellular signaling, inflammation, and other physiological processes.
• Fine Chemical Synthesis: Acts as a building block for the production of more complex, high-value specialty chemicals and potential drug candidates.
• Analytical Standard: Employed as a certified reference material (CRM) for method development, validation, and quality control in analytical laboratories.

Basic Information

Product Name	11-Deoxy-16,16-Dimethyl Prostaglandin E2
CAS No.	53658-98-3
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	16,16-Dimethyl-11-deoxyprostaglandin E2; 16,16-Dimethyl-PGE2; 11-Deoxy-16,16-dimethyl-PGE2; 9-Oxo-11α,15α-dihydroxy-16,16-dimethyl-5-cis,13-trans-prostadienoic acid; DM-PGE2; 16,16-Dimethyl-9-oxoprosta-5,13-dien-1-oic acid; (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxy-16,16-dimethylprosta-5,13-dien-1-oic acid
EINECS	Contact for details

Quality Control

Our 11-Deoxy-16,16-Dimethyl Prostaglandin E2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.