Description

1-(3-Trifluoromethyl-Phenyl)-Pyrrole-2,5-Dione is a specialized heterocyclic building block featuring a maleimide core substituted with a trifluoromethylphenyl group. This compound matters for its unique chemical reactivity and the valuable properties imparted by the trifluoromethyl moiety, such as enhanced lipophilicity and metabolic stability. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the CF3 group can improve biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or chemical resistance.
• Bioconjugation Chemistry: The maleimide group is reactive towards thiols, making it useful for labeling proteins, peptides, and other biomolecules.
• Organic Electronic Materials: Investigated as a component in the synthesis of organic semiconductors or charge-transport materials.
• Chemical Biology Probes: Utilized in the design of activity-based probes and inhibitors for studying enzyme function.

Basic Information

Product Name	1-(3-Trifluoromethyl-Phenyl)-Pyrrole-2,5-Dione
CAS No.	53629-19-9
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	3-(Trifluoromethyl)phenylmaleimide; 1-[3-(Trifluoromethyl)phenyl]-1H-pyrrole-2,5-dione; N-(3-Trifluoromethylphenyl)maleimide; 3-Trifluoromethylphenylmaleimide; m-Trifluoromethylphenylmaleimide; Maleimide, N-(m-trifluoromethylphenyl)-; 1-(3-(Trifluoromethyl)phenyl)-1H-pyrrole-2,5-dione
EINECS	Contact for details

Quality Control

Our 1-(3-Trifluoromethyl-Phenyl)-Pyrrole-2,5-Dione is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided and available upon request, supporting your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.