Description

1-O,2-O,3-O,4-O,5-o-Pentakis(Trimethylsilyl)-6-Deoxy-D-Glucitol is a fully silylated derivative of 6-deoxy-D-glucitol, a protected sugar alcohol. This compound is a valuable intermediate and protecting group reagent in advanced organic synthesis, particularly for modifying carbohydrate structures. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleoside analogs, antiviral agents, and other complex bioactive molecules.
• Carbohydrate Chemistry Reagent: Used for the protection of hydroxyl groups during the multi-step synthesis of oligosaccharides and glycoconjugates.
• Chiral Pool Synthesis: Serves as a chiral template or starting material for the asymmetric synthesis of natural products and fine chemicals.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, or plant growth regulators with specific stereochemistry.
• Material Science: Potential monomer or modifier in the creation of specialized polymers with unique properties.
• Analytical Standard: Used as a reference standard in chromatographic analysis (GC, HPLC) for quality control and method development.

Basic Information

Product Name	1-O,2-O,3-O,4-O,5-o-Pentakis(Trimethylsilyl)-6-Deoxy-D-Glucitol
CAS No.	53537-99-8
Molecular Formula	C24H58O5Si5
Molecular Weight	583.18 g/mol
Synonyms	6-Deoxy-D-glucitol pentakis(trimethylsilyl) ether; D-Glucitol, 6-deoxy-, 1,2,3,4,5-pentakis-O-(trimethylsilyl)-; Pentakis-O-trimethylsilyl-6-deoxy-D-glucitol; 1,2,3,4,5-Penta-O-trimethylsilyl-6-deoxy-D-glucitol; Fully protected 6-deoxyglucitol; TMS-protected 6-deoxy-D-glucitol; Hexitol silyl ether derivative
EINECS	Contact for details

Quality Control

Our 1-O,2-O,3-O,4-O,5-o-Pentakis(Trimethylsilyl)-6-Deoxy-D-Glucitol is produced under controlled conditions to ensure high chemical purity and consistency. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and optical rotation analysis, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Typical 97-99%)
Optical Rotation [α]	Contact for details
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.