Description

4-Bromobenzylsulfonyl Chloride is a versatile and reactive organosulfur compound that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, acting as a sulfonylating agent and providing a brominated aromatic handle for further cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and advanced organic materials.
• Chemical Biology Probes: Employed in the design of activity-based probes for studying enzyme function and protein labeling.
• Cross-Coupling Reactions: The bromoaryl group facilitates Suzuki, Stille, and other palladium-catalyzed coupling reactions to create complex biaryl structures.
• Sulfonylation Agent: Reacts with amines and alcohols to introduce the sulfonyl functional group, a common motif in bioactive molecules.

Basic Information

Product Name	4-Bromobenzylsulfonyl Chloride
CAS No.	53531-69-4
Molecular Formula	C7H6BrClO2S
Molecular Weight	269.54 g/mol
Synonyms	p-Bromobenzylsulfonyl Chloride; 1-(Bromomethyl)-4-chlorosulfonylbenzene; 4-Bromophenylmethanesulfonyl Chloride; (4-Bromophenyl)methanesulfonyl Chloride; α-Bromo-p-toluenesulfonyl Chloride; Benzenemethanesulfonyl Chloride, 4-bromo-; Bromobenzyl Sulfonyl Chloride
EINECS	Contact for details

Quality Control

Every batch of our 4-Bromobenzylsulfonyl Chloride is produced and tested under a strict quality management system. We ensure high purity and consistency to meet the exacting standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.