Description

m-Tolylmethanesulfonyl Chloride is a specialized organic sulfonyl chloride derivative, serving as a critical reagent in advanced chemical synthesis. Its primary value lies in its role as a versatile sulfonylation and mesylation agent, enabling the introduction of the tosyl-like protecting group or the creation of sulfonamide linkages. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of sulfonamide-based drugs and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents requiring sulfonyl functional groups.
• Peptide Chemistry: Acts as a protecting group for amines during complex peptide synthesis.
• Polymer Science: Monomer or modifying agent for creating specialty polymers with specific sulfonyl properties.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of sulfonated dyes and colorants.
• Organic Synthesis Reagent: Versatile reagent for sulfonylation reactions in academic and industrial R&D laboratories.

Basic Information

Product Name	m-Tolylmethanesulfonyl Chloride
CAS No.	53531-68-3
Molecular Formula	C8H9ClO2S
Molecular Weight	204.67 g/mol
Synonyms	3-Methylbenzenemethanesulfonyl Chloride; m-Toluenemethanesulfonyl Chloride; (3-Methylphenyl)methanesulfonyl Chloride; α-Toluenesulfonyl Chloride, 3-Methyl-; m-Tosyl Chloride (common); m-Tolylmethylsulfonyl Chloride; Mesyl Chloride, m-Tolyl Derivative
EINECS	Contact for details

Quality Control

Our m-Tolylmethanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.