Description

(3β,20E)-24-Norchola-5,20(22)-Diene-3,23-Diol is a high-purity steroidal diol derivative, serving as a critical advanced intermediate in pharmaceutical research and synthesis. Its unique norcholane structure with conjugated diene and diol functionalities makes it a valuable building block for developing novel therapeutic agents and bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors focused on steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel steroid-based drugs and hormone analogs.
• Biochemical Research: Used as a reference standard and probe in metabolic pathway studies and receptor binding assays.
• Fine Chemical Synthesis: Serves as a versatile chiral building block for the synthesis of complex natural products and specialty chemicals.
• Academic & R&D Laboratories: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Development: Used in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(3β,20E)-24-Norchola-5,20(22)-Diene-3,23-Diol
CAS No.	53495-21-9
Molecular Formula	C23H34O2
Molecular Weight	342.52 g/mol
Synonyms	(3β,20E)-24-Norchola-5,20(22)-diene-3,23-diol; 24-Norchola-5,20(22)-diene-3β,23-diol; (20E)-3β,23-Dihydroxy-24-norchola-5,20(22)-diene; 3β,23-Dihydroxynorchola-5,20(22)-diene; Steroid Diol Intermediate; Norcholadienediol; 53495-21-9
EINECS	Contact for details

Quality Control

Our (3β,20E)-24-Norchola-5,20(22)-Diene-3,23-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for research and development use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.