Description

3-Formylbenzenesulfonyl Chloride is a versatile aromatic sulfonyl chloride derivative featuring a reactive formyl group, making it a key bifunctional building block in organic synthesis. Its primary value lies in its dual functionality, allowing for sequential or selective modifications to create complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing sulfonamide-based active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel sulfonamide drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to construct active ingredients for herbicides, fungicides, and pesticides that require the sulfonamide pharmacophore.
• Dyestuff and Pigment Manufacturing: Serves as a key intermediate for producing sulfonated dyes and colorants with enhanced properties.
• Polymer Chemistry: Employed in the creation of functionalized polymers and resins, where the sulfonyl chloride group enables cross-linking or grafting.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry for constructing compound libraries and exploring new synthetic routes.
• Ligand and Catalyst Design: Useful for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	3-Formylbenzenesulfonyl Chloride
CAS No.	53460-88-1
Molecular Formula	C7H5ClO3S
Molecular Weight	204.63 g/mol
Synonyms	3-Formylbenzenesulfonyl chloride; m-Formylbenzenesulfonyl chloride; 3-Carboxybenzenesulfonyl chloride (precursor-related); m-Carboxybenzene-1-sulfonyl chloride; 3-(Chlorosulfonyl)benzaldehyde; Benzaldehyde, 3-(chlorosulfonyl)-; Meta-formyl phenyl sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Formylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.