Description

2,3-Iminosqualene is a synthetic, nitrogen-containing analog of the natural triterpene squalene, serving as a key intermediate in the development of novel pharmaceutical agents. Its primary value lies in its role as a potent and selective inhibitor of the enzyme squalene epoxidase, a critical target in cholesterol biosynthesis and fungal ergosterol production. This compound is therefore essential for researchers and manufacturers in the pharmaceutical and life sciences sectors, particularly those focused on developing new cholesterol-lowering drugs, antifungal agents, and enzyme mechanism studies.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel therapeutic agents targeting cholesterol metabolism.
• Enzyme Inhibition Studies: Used as a reference standard and tool compound in biochemical research to study squalene epoxidase inhibition and sterol biosynthesis pathways.
• Antifungal Drug Development: Serves as a precursor or model compound for developing new classes of antifungal medications that disrupt fungal cell membrane integrity.
• Biochemical Research: Employed in academic and industrial R&D to investigate isoprenoid biosynthesis and enzyme kinetics.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical products.

Basic Information

Product Name	2,3-Iminosqualene
CAS No.	53402-48-5
Molecular Formula	C30H51N
Molecular Weight	425.74 g/mol
Synonyms	2,3-Iminosqualene; (3E,7E,11E,15E,19E,23E)-2-Aza-2,3-dihydrosqualene; 2-Azasqualene; Squalene 2,3-imine; 2,3-Didehydrosqualenimine; NSC 338950; Squalene Epoxidase Inhibitor (Analog)
EINECS	Contact for details

Quality Control

Our 2,3-Iminosqualene is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.