Description

Urushiol is the primary active irritant compound found in plants of the Toxicodendron genus, such as poison ivy, poison oak, and poison sumac. This compound is of significant interest due to its role in causing allergic contact dermatitis, making it a critical subject for research in dermatology, immunology, and the development of protective treatments. It is essential for laboratories and manufacturers focused on studying allergic responses, developing diagnostic tests, or formulating barrier creams and cleansers. Our supply of Urushiol CAS NO 53237-59-5 ensures high purity and consistency for these demanding applications.

Application

• Allergen Research: Used as a standard reference material in immunological studies to understand and characterize Type IV hypersensitivity reactions (allergic contact dermatitis).
• Diagnostic Development: Serves as a key component in the research and formulation of patch tests for diagnosing specific plant-induced allergies.
• Pharmaceutical R&D: Employed in the screening and evaluation of potential topical treatments, barrier formulations, and cleansing agents designed to prevent or mitigate skin reactions.
• Toxicological Studies: Acts as a model compound for investigating skin penetration, irritation mechanisms, and the efficacy of decontamination protocols.
• Biochemical Reagent: Utilized in enzymatic studies and as a substrate or inhibitor in specific biochemical assays related to skin metabolism.
• Material Science: Investigated for its unique chemical properties in specialized coating or adhesive research, inspired by its natural role.

Basic Information

Product Name	Urushiol
CAS No.	53237-59-5
Molecular Formula	C21H32O2 (for a common congener; mixture of catechol derivatives with unsaturated side chains)
Molecular Weight	Variable (approx. 316.5 g/mol for a C21 congener)
Synonyms	3-Pentadecylcatechol (common component); 1,2-Dihydroxy-3-pentadecylbenzene; Poison Ivy Urushiol; Toxicodendron Resin; Rhus Toxicodendron Extract; Laccol (related compound); 3-Heptadecylcatechol; 3-(8Z,11Z-Heptadecadienyl)catechol
EINECS	Contact for details

Quality Control

Our Urushiol is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for research purposes. While it is typically offered as a natural mixture reflective of its plant source, specific grades can be characterized by HPLC to profile major congeners. A comprehensive Certificate of Analysis (COA) detailing identification, assay, and purity is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. For long-term stability, keep the container in a freezer at -20°C. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (HPLC)	Conforms to reference profile
Assay (Total Urushiols by HPLC)	≥ 95%
Solubility	Soluble in ethanol, ether, benzene; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.