Description

Fagomine CAS NO 53185-12-9 is a naturally occurring iminosugar, specifically a polyhydroxylated piperidine alkaloid, known for its potent glycosidase inhibitory activity. This compound is of significant interest in pharmaceutical research and development due to its ability to modulate carbohydrate-processing enzymes. It is primarily sought by researchers and manufacturers in the life sciences sector for applications in drug discovery, biochemical studies, and as a potential therapeutic agent for metabolic and viral diseases.

Application

• Pharmaceutical Research: As a key intermediate or reference standard in the development of glycosidase inhibitors for treating diabetes, Gaucher's disease, and viral infections like influenza and HIV.
• Biochemical Tool: Used in enzymatic studies to investigate the mechanism of action of α-glucosidases and other carbohydrate-processing enzymes.
• Glycobiology Studies: Employed in research focused on carbohydrate metabolism, glycoprotein processing, and cell signaling pathways.
• Antiviral Agent Development: Investigated for its potential to inhibit viral glycosidases, which are crucial for viral replication and infectivity.
• Chemical Synthesis: Serves as a chiral building block for the synthesis of more complex iminosugar derivatives and glycomimetics.
• Academic Research: Utilized in universities and research institutes for fundamental studies in medicinal chemistry and enzymology.

Basic Information

Product Name	Fagomine
CAS No.	53185-12-9
Molecular Formula	C7H15NO4
Molecular Weight	177.20 g/mol
Synonyms	1,5-Dideoxy-1,5-imino-D-mannitol; (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol; D-Fagomine; Fagomine base; 1-Deoxymannojirimycin isomer; 1,5-Dideoxy-1,5-imino-D-mannitol; Polyhydroxypiperidine alkaloid
EINECS	Contact for details

Quality Control

Our Fagomine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data including HPLC purity, chiral purity, and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting compliance with our stringent in-house specifications. For custom synthesis or specific grade requirements, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.