Description

Deacetylnorgestimate (25 Mg) ((E)- And (Z)-17-Deacetyl Norgestimate Mixture) is a high-purity synthetic steroid intermediate, specifically a mixture of its (E)- and (Z)- isomers. This compound is a critical precursor in the pharmaceutical synthesis of norgestimate, a key progestin used in hormonal contraceptives and hormone replacement therapies. It is essential for research and development laboratories, process chemists, and manufacturers in the global pharmaceutical and fine chemical industries who require a reliable, high-quality building block for complex organic synthesis.

Application

• Pharmaceutical Intermediate: Primary use as a key synthetic precursor in the commercial production of the progestin Norgestimate.
• Active Pharmaceutical Ingredient (API) Development: Serves as a critical starting material or intermediate in the R&D and scale-up of steroidal APIs.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling of norgestimate-based drug products.
• Process Chemistry Research: Employed in academic and industrial research to study stereoselective synthesis pathways and optimize manufacturing processes for steroidal compounds.
• Hormone Research: Utilized in biochemical research to investigate the structure-activity relationships of synthetic progestins and their metabolites.

Basic Information

Product Name	Deacetylnorgestimate (25 Mg) ((E)- And (Z)-17-Deacetyl Norgestimate Mixture)
CAS No.	53016-31-2
Molecular Formula	C₂₀H₂₅NO₃
Molecular Weight	327.42 g/mol
Synonyms	17-Deacetyl Norgestimate; (17R)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one oxime; 17-Deacetylnorgestimate; Norgestimate Impurity C (EP); Norgestimate Related Compound C (USP); (E/Z)-17-Deacetylnorgestimate; 17-Desacetylnorgestimate; 3-(Ethinyl)-13-ethyl-17-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one oxime
EINECS	Contact for details

Quality Control

Our Deacetylnorgestimate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for assay and impurity profiling, to ensure it meets exacting standards for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, isomer ratio, and specific tests are provided with every shipment. We support compliance with ICH guidelines and can supply material suitable for use under current Good Manufacturing Practice (cGMP) conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Isomer Ratio ((E)-/(Z)-) (HPLC)	As per customer requirement
Related Substances (HPLC)	Individual unknown impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.