Description

Trichloroacetic Acid, [1-14C] CAS NO 52845-17-7 is a carbon-14 labeled isotopologue of trichloroacetic acid, a potent halogenated organic acid. This radiolabeled compound is essential for precise metabolic and environmental fate studies, enabling researchers to track molecular pathways with high specificity. It is primarily required by pharmaceutical R&D laboratories, agrochemical companies, and environmental science institutions conducting advanced tracer experiments and analytical method development.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer in pharmacokinetic and drug metabolism studies to elucidate biotransformation pathways.
• Environmental Degradation Studies: Employed to investigate the fate and breakdown products of trichloroacetic acid and related compounds in ecological systems.
• Biochemical Research: Serves as a tool in enzymatic studies and protein precipitation experiments where tracking is necessary.
• Analytical Method Development: Acts as a critical standard in developing and validating sensitive LC-MS/MS, HPLC, or scintillation counting methods.
• Agrochemical Research: Utilized in studies to understand the metabolism and residue profile of chlorinated agrochemicals.
• Chemical Synthesis Intermediate: Provides a labeled building block for the synthesis of more complex carbon-14 labeled molecules for research.

Basic Information

Product Name	Trichloroacetic Acid, [1-14C]
CAS No.	52845-17-7
Molecular Formula	C14Cl3COOH / C14CCl3COOH
Molecular Weight	~163.38 g/mol (for 12C form; exact mass varies with isotopic enrichment)
Synonyms	Trichloroacetic-1-14C Acid; [1-14C]Trichloroacetic Acid; TCA-14C; Carbon-14 Labeled Trichloroacetic Acid; 2,2,2-Trichloroacetic-1-14C Acid; Acetic Acid, 2,2,2-Trichloro-, (1-14C)-; Radiolabeled TCA
EINECS	Contact for details

Quality Control

Every batch of Trichloroacetic Acid, [1-14C] is manufactured and analyzed under strict quality systems. Certificates of Analysis (COA) are provided, detailing critical parameters such as radiochemical purity, chemical purity, specific activity, and solvent composition. Our quality commitment ensures the material meets the stringent requirements for reliable research use. Certificates are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and a strong acid/organic solvent. Handle and store in accordance with all applicable radiation safety and laboratory chemical hygiene regulations.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR/NMR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	Contact for details (mCi/mmol)
Solvent	Specified on COA (e.g., aqueous solution, specific buffer)
Concentration	Specified on COA (e.g., μCi/mL, mg/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.