Description

Vasopressin, Deamino-Homo-Arg- is a synthetic analogue of the endogenous neurohypophysial hormone vasopressin, characterized by the deamination of the N-terminal cysteine and the substitution of arginine with homoarginine at position 8. This modification enhances its metabolic stability and receptor binding affinity, making it a valuable research tool for studying vasopressin receptor subtypes and their physiological roles. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in neuroendocrinology, cardiovascular research, and the development of novel therapeutic agents.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies targeting V1a and V2 vasopressin receptors to understand their signaling pathways.
• Biochemical Assay Development: Serves as a critical ligand in receptor binding assays, competitive inhibition studies, and functional cell-based tests.
• Endocrinology Studies: Investigates the role of vasopressin analogues in fluid balance, blood pressure regulation, and stress response mechanisms.
• Drug Discovery & Development: Acts as a lead compound or intermediate for the design and synthesis of new peptide-based therapeutics with improved pharmacokinetic profiles.
• Academic & Clinical Research: Supports fundamental research into central nervous system disorders, renal function, and cardiovascular diseases.

Basic Information

Product Name	Vasopressin, Deamino-Homo-Arg-
CAS No.	52697-47-9
Molecular Formula	C48H70N16O12S2
Molecular Weight	1119.3 g/mol
Synonyms	Deamino-[8-homoarginine]-vasopressin; dDAVP analogue; 1-Desamino-8-homoarginine vasopressin; [HomoArg8]-dDAVP; Desmopressin homoarginine analogue; Vasopressin, 1-deamino-8-homoarginine-; [Mpa1, HomoArg8]-VP
EINECS	Contact for details

Quality Control

Our Vasopressin, Deamino-Homo-Arg- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and specific tests for related substances. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.