Description

1,3-Bis(Chlorodifluoromethyl)Benzene is a high-purity, specialty fluorinated aromatic compound. This chemical serves as a critical building block and intermediate in advanced organic synthesis, valued for its unique difluoromethyl and chlorodifluoromethyl functional groups. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the introduction of fluorine atoms improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a fluorinated building block for electronic chemicals used in display and lighting technologies.
• Polymer & Resin Modification: Incorporated into specialty polymers to impart specific properties such as chemical resistance, low surface energy, or altered refractive index.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a source of the chlorodifluoromethyl group in medicinal and materials chemistry.
• Chemical Research & Development: A valuable tool for academic and industrial researchers exploring new fluorination methodologies and compound libraries.

Basic Information

Product Name	1,3-Bis(Chlorodifluoromethyl)Benzene
CAS No.	52695-47-3
Molecular Formula	C8H4Cl2F4
Molecular Weight	247.02 g/mol
Synonyms	1,3-Bis(chlorodifluoromethyl)benzene; α,α,α',α'-Tetrachloro-1,3-xylene; 1,3-Bis(trichloromethyl)benzene (incorrect but common misnomer); m-Xylylene Hexachloride (related); Benzene, 1,3-bis(chlorodifluoromethyl)-; 1,3-Di(chlorodifluoromethyl)benzene; m-Bis(chlorodifluoromethyl)benzene; NSC 406924
EINECS	Contact for details

Quality Control

Our 1,3-Bis(Chlorodifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with relevant regulatory frameworks for industrial and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.