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(5Z,13E,15S,17Z)-15-Hydroxy-9-Oxoprosta-5,11,13,17-Tetraen-1-Oic Acid CAS NO 52590-97-3
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CAS No.:52590-97-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(5Z,13E,15S,17Z)-15-Hydroxy-9-Oxoprosta-5,11,13,17-Tetraen-1-Oic Acid is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its precise stereochemistry and biological activity, making it essential for studying inflammatory pathways and developing targeted therapeutics. It is primarily utilized by pharmaceutical companies, biotechnology research institutions, and academic laboratories engaged in drug discovery and biochemical synthesis.
Application
- Pharmaceutical Intermediate: Critical starting material or intermediate in the synthesis of novel prostaglandin-based drugs targeting inflammation, pain, and cardiovascular conditions.
- Biochemical Research: Used as a reference standard and active agent in in vitro and in vivo studies to investigate eicosanoid signaling, receptor binding, and enzyme inhibition.
- Drug Discovery & Development: Serves as a core scaffold for medicinal chemistry programs aimed at creating new chemical entities with optimized potency and selectivity.
- Academic Research: Employed in university and institutional labs for fundamental studies on arachidonic acid metabolism and the role of specific prostaglandin metabolites.
- Reference Standard: High-purity grade suitable for use as an analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and method validation.
Basic Information
| Product Name | (5Z,13E,15S,17Z)-15-Hydroxy-9-Oxoprosta-5,11,13,17-Tetraen-1-Oic Acid |
| CAS No. | 52590-97-3 |
| Molecular Formula | C₂₀H₂₈O₄ |
| Molecular Weight | 332.43 g/mol |
| Synonyms | 15(S)-15-Hydroxy-9-oxoprosta-5Z,11,13E,17Z-tetraenoic acid; 9-Keto-15(S)-hydroxyprosta-5Z,11,13E,17Z-tetraenoic acid; 15(S)-HETE lactone derivative; Prostaglandin A2 analog; PGA2 derivative; 9-Oxo-15(S)-HETE; 15-Hydroxy-9-oxoprosta-5,11,13,17-tetraenoic acid |
| EINECS | Contact for details |
Quality Control
Our (5Z,13E,15S,17Z)-15-Hydroxy-9-Oxoprosta-5,11,13,17-Tetraen-1-Oic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to verify stereochemical integrity. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake. Keep away from strong oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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