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(5Z,13E,15S,17Z)-15-Hydroxy-9-Oxoprosta-5,11,13,17-Tetraen-1-Oic Acid CAS NO 52590-97-3


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CAS No.:52590-97-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(5Z,13E,15S,17Z)-15-Hydroxy-9-Oxoprosta-5,11,13,17-Tetraen-1-Oic Acid is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its precise stereochemistry and biological activity, making it essential for studying inflammatory pathways and developing targeted therapeutics. It is primarily utilized by pharmaceutical companies, biotechnology research institutions, and academic laboratories engaged in drug discovery and biochemical synthesis.

Application

  • Pharmaceutical Intermediate: Critical starting material or intermediate in the synthesis of novel prostaglandin-based drugs targeting inflammation, pain, and cardiovascular conditions.
  • Biochemical Research: Used as a reference standard and active agent in in vitro and in vivo studies to investigate eicosanoid signaling, receptor binding, and enzyme inhibition.
  • Drug Discovery & Development: Serves as a core scaffold for medicinal chemistry programs aimed at creating new chemical entities with optimized potency and selectivity.
  • Academic Research: Employed in university and institutional labs for fundamental studies on arachidonic acid metabolism and the role of specific prostaglandin metabolites.
  • Reference Standard: High-purity grade suitable for use as an analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and method validation.

Basic Information

Product Name (5Z,13E,15S,17Z)-15-Hydroxy-9-Oxoprosta-5,11,13,17-Tetraen-1-Oic Acid
CAS No. 52590-97-3
Molecular Formula C₂₀H₂₈O₄
Molecular Weight 332.43 g/mol
Synonyms 15(S)-15-Hydroxy-9-oxoprosta-5Z,11,13E,17Z-tetraenoic acid; 9-Keto-15(S)-hydroxyprosta-5Z,11,13E,17Z-tetraenoic acid; 15(S)-HETE lactone derivative; Prostaglandin A2 analog; PGA2 derivative; 9-Oxo-15(S)-HETE; 15-Hydroxy-9-oxoprosta-5,11,13,17-tetraenoic acid
EINECS Contact for details

Quality Control

Our (5Z,13E,15S,17Z)-15-Hydroxy-9-Oxoprosta-5,11,13,17-Tetraen-1-Oic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to verify stereochemical integrity. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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