Description

Prostaglandin H1 is a key intermediate in the biosynthesis of other prostaglandins and thromboxanes, representing a critical point in the arachidonic acid cascade. This compound is essential for researchers and manufacturers developing pharmaceuticals targeting inflammation, pain, and cardiovascular function. It is primarily utilized in advanced biochemical research, reference standard preparation, and the synthesis of more complex bioactive lipid mediators.

Application

• Biochemical Research: Used as a critical intermediate to study the cyclooxygenase pathway and eicosanoid metabolism.
• Pharmaceutical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in drug discovery.
• Precursor Synthesis: A vital starting material or intermediate in the organic synthesis of downstream prostaglandins (e.g., PGD2, PGE2, PGF2α) and thromboxane A2.
• Cell Signaling Studies: Employed in vitro to investigate the role of prostaglandin intermediates in cellular signaling and physiological responses.
• Enzyme Activity Assays: Used as a substrate to measure and characterize the activity of specific enzymes like prostaglandin synthases.

Basic Information

Item	Detail
Product Name	Prostaglandin H1
CAS No.	52589-22-7
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	PGH1; (5Z,13E)-(15S)-9α,11α-Epidioxy-15-hydroxyprosta-5,13-dien-1-oic acid; 9α,11α-Epidioxy-15(S)-hydroxy-(5Z,13E)-prostadienoic acid; Prostaglandin G1 (common misnomer); 15(S)-Hydroxy-9α,11α-peroxidoprosta-5,13-dienoic acid; Cyclic peroxide intermediate of PGE1
EINECS	Contact for details

Quality Control

Our Prostaglandin H1 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.