Description

1-Bromo-2,3-Dimethyl-4-Fluorobenzene is a high-purity halogenated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective functionalization and the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated, multi-substituted benzene core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the bromine and fluorine atoms provide specific biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as liquid crystals and semiconductor precursors, where its structure influences material properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of the bromine atom.
• Fine Chemical Production: Used in custom and contract manufacturing for producing specialty chemicals and complex organic molecules.

Basic Information

Product Name	1-Bromo-2,3-Dimethyl-4-Fluorobenzene
CAS No.	52548-00-2
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	2,3-Dimethyl-4-fluorobromobenzene; 4-Fluoro-2,3-dimethylbromobenzene; 2-Bromo-1,4-dimethyl-5-fluorobenzene; 4-Fluoro-2,3-dimethylphenyl bromide; Benzene, 1-bromo-2,3-dimethyl-4-fluoro-; 52548-00-2 (CAS)
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,3-Dimethyl-4-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.