Description

n-Acetylprostaglandin E2 Carboxamide is a chemically modified derivative of prostaglandin E2, designed for enhanced stability and specific biological activity. This compound is a critical intermediate and research tool for developing novel therapeutic agents targeting inflammation, pain, and cellular proliferation. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in advanced prostaglandin research and drug discovery programs.

Application

• Pharmaceutical Research & Development: Serves as a key synthetic intermediate in the development of new anti-inflammatory and cytoprotective drugs.
• Biochemical Research: Used as a reference standard and probe compound to study prostaglandin receptor (EP) signaling pathways and their physiological roles.
• Drug Discovery: Acts as a precursor for creating analogs with improved pharmacokinetic profiles, such as enhanced metabolic stability or tissue selectivity.
• Cell Biology Studies: Employed in *in vitro* assays to investigate its effects on cell growth, differentiation, and apoptosis in various cell lines.
• Academic Research: A valuable tool for universities and research institutes exploring the chemistry and biology of eicosanoids.

Basic Information

Product Name	n-Acetylprostaglandin E2 Carboxamide
CAS No.	52533-44-5
Molecular Formula	C24H37NO6
Molecular Weight	435.56 g/mol
Synonyms	N-Acetyl-PGE2 carboxamide; 11α,15α-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid N-acetyl amide; PGE2 N-acetyl carboxamide; 9-Oxo-11α,15α-dihydroxyprosta-5,13-dien-1-oic acid N-acetyl amide; Acetylprostaglandin E2 carboxamide; Prostaglandin E2 N-acetyl carboxamide derivative; n-Acetyl PGE2 amide
EINECS	Contact for details

Quality Control

Our n-Acetylprostaglandin E2 Carboxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity determination and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and related substance profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.