Description

Tetranor-Pgam is a high-purity synthetic prostaglandin metabolite, identified by CAS No. 52510-53-9. This compound serves as a critical reference standard and intermediate in advanced pharmaceutical research and development. It is essential for scientists and manufacturers in the life sciences sector requiring precise analytical and synthetic materials.

Application

• Pharmaceutical Reference Standard: Used for the quantification and qualification of prostaglandin-related compounds in drug development and bioanalytical studies.
• Biochemical Research: Employed as a key metabolite in studies investigating eicosanoid pathways, inflammation, and cellular signaling mechanisms.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a sophisticated building block in the multi-step synthesis of novel therapeutic agents.
• Diagnostic Kit Manufacturing: Utilized in the production of calibration standards for immunoassays and clinical diagnostic tests targeting prostaglandin metabolites.
• Academic Research: A vital tool for universities and research institutions studying reproductive biology, renal function, and cardiovascular pharmacology.
• Quality Control Laboratories: Acts as a system suitability standard in HPLC and LC-MS/MS methods to ensure analytical accuracy and method validation.

Basic Information

Product Name	Tetranor-Pgam
CAS No.	52510-53-9
Molecular Formula	C16H28O5
Molecular Weight	300.39 g/mol
Synonyms	7α-Hydroxy-5,11-diketotetranorprosta-1,16-dioic Acid; 13,14-Dihydro-15-keto-tetranor-PGEM; Tetranor Prostaglandin E Metabolite; Tetranor PGEM; 5,11-Dioxo-9,15-dihydroxy-2,3,4,5-tetranorprostan-1,20-dioic Acid; PGE-M; 7α-Hydroxy-5,11-diketotetranorprostane-1,16-dioic Acid
EINECS	Contact for details

Quality Control

Every batch of Tetranor-Pgam is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and guarantee product integrity for research and cGMP applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and strength is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.