Description

2-Chloro-5-Trifluoromethylpyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, provides exceptional reactivity and lipophilicity, making it indispensable for creating complex molecules. This intermediate is primarily sought by the agrochemical and pharmaceutical industries for the development of novel active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, insecticides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry for constructing drug candidates, particularly in areas targeting central nervous system (CNS) disorders and anti-infective agents.
• Liquid Crystal & Electronic Chemicals: Employed in the production of specialty materials for display technologies and electronic applications due to its stable aromatic fluorine chemistry.
• Organic Synthesis Reagent: Functions as a versatile reactant for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions to introduce the 2-chloro-5-trifluoromethylpyridyl moiety.
• Research & Development: Utilized in academic and industrial R&D labs for exploring new chemical entities and synthetic pathways.

Basic Information

Product Name	2-Chloro-5-Trifluoromethylpyridine
CAS No.	52334-81-3
Molecular Formula	C6H3ClF3N
Molecular Weight	181.54 g/mol
Synonyms	2-Chloro-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-chloropyridine; 2-Chloro-α,α,α-trifluoro-5-picoline; 2-Chloro-5-trifluoromethyl pyridine; 2-Chloro-5-(trifluoromethyl)pyridine; 2-Chloro-5-(trifluoromethyl)azine; Pyridine, 2-chloro-5-(trifluoromethyl)-
EINECS	257-842-4

Quality Control

Our 2-Chloro-5-Trifluoromethylpyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.