Description

4-Chloro-2,3,5,6-Tetrafluoropyridine is a versatile fluorinated pyridine derivative, serving as a critical building block in advanced chemical synthesis. Its value lies in the unique reactivity imparted by the chlorine and fluorine substituents, enabling precise molecular modifications. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its fluorinated structure for enhanced bioactivity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and catalysts used in cross-coupling and other metal-mediated reactions.
• Material Science: Incorporated into the synthesis of specialty polymers, liquid crystals, and electronic materials to modify their physical and chemical properties.
• Organic Synthesis Building Block: Employed in nucleophilic aromatic substitution and other reactions to introduce the tetrafluoropyridine scaffold into complex molecules.

Basic Information

Product Name	4-Chloro-2,3,5,6-Tetrafluoropyridine
CAS No.	52026-98-9
Molecular Formula	C5HClF4N
Molecular Weight	183.51 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-chloropyridine; 4-Chloro-2,3,5,6-tetrafluoropyridine; Perfluoro-4-chloropyridine; Tetrafluoro-4-chloropyridine; Pyridine, 4-chloro-2,3,5,6-tetrafluoro-; 4-Chlorotetrafluoropyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,3,5,6-Tetrafluoropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Handle and store in accordance with all applicable regulations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.