Description

1,4-Dideoxy-1,4-Imino-D-Xylitol Hydrochloride is a high-purity, synthetic iminosugar derivative of significant interest in pharmaceutical and biochemical research. This compound serves as a potent and selective glycosidase inhibitor, making it a valuable tool for studying carbohydrate metabolism and enzyme function. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics for metabolic disorders, viral infections, and as a chemical probe in glycobiology. Its well-defined structure and biological activity underpin its role in advancing targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of more complex therapeutic agents targeting glycosidases.
• Biochemical Research: Used as a selective inhibitor in enzymatic studies to investigate the mechanisms of carbohydrate-processing enzymes like α-glucosidases.
• Drug Discovery: Employed in high-throughput screening and lead optimization for diseases such as diabetes, viral infections (e.g., HIV, influenza), and lysosomal storage disorders.
• Glycobiology Studies: Acts as a chemical probe to disrupt glycosylation pathways, helping to elucidate the role of glycans in cellular communication and disease.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	1,4-Dideoxy-1,4-Imino-D-Xylitol Hydrochloride
CAS No.	52019-89-3
Molecular Formula	C5H12ClNO3
Molecular Weight	169.61 g/mol
Synonyms	1,4-Dideoxy-1,4-imino-D-xylitol HCl; DAB hydrochloride; 1,4-Dideoxy-1,4-iminoxylitol hydrochloride; (2R,3R,4R)-2-(Hydroxymethyl)piperidine-3,4-diol hydrochloride; 1,4-Dideoxy-1,4-iminopentitol hydrochloride; Iminosugar derivative hydrochloride; Glycosidase inhibitor intermediate; DIX hydrochloride
EINECS	Contact for details

Quality Control

Our 1,4-Dideoxy-1,4-Imino-D-Xylitol Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant guidelines for fine chemical production, and specifications can be tailored to meet the stringent requirements of pharmaceutical development (e.g., ICH guidelines).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.