Description

Prostaglandin G2 is a critical intermediate in the arachidonic acid cascade, serving as the direct precursor to prostaglandin H2 via the cyclooxygenase pathway. This compound is essential for biochemical research focused on understanding eicosanoid biosynthesis, inflammation mechanisms, and cellular signaling. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers for developing analytical standards and studying enzyme kinetics.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in studies of prostaglandin biosynthesis and cyclooxygenase (COX) enzyme activity.
• Pharmaceutical Development: Serves as a key intermediate in research aimed at developing novel anti-inflammatory and analgesic therapeutics.
• Cell Signaling Studies: Employed to investigate the role of prostaglandin intermediates in cellular communication, inflammation, and immune responses.
• Enzyme Assay Substrate: Acts as a specific substrate for in vitro assays to measure the activity and inhibition of prostaglandin-endoperoxide synthase.
• Diagnostic Reagent Manufacturing: Utilized in the production of calibrators and controls for diagnostic kits targeting inflammatory biomarkers.
• Metabolic Pathway Analysis: Critical for tracing metabolic pathways in lipidomics and eicosanoid profiling research.

Basic Information

Product Name	Prostaglandin G2
CAS No.	51982-36-6
Molecular Formula	C₂₀H₃₂O₆
Molecular Weight	368.47 g/mol
Synonyms	PGG2; Prostaglandin G2; (5Z,9α,11α,13E,15S)-9,11-Epidioxy-15-hydroxyprosta-5,13-dien-1-oic acid; 9α,11α-Epidioxy-15(S)-hydroxyprosta-5Z,13E-dien-1-oic acid; 15-Hydroxy-9α,11α-peroxidoprosta-5,13-dienoic acid; 9,11-Epidioxy-15-hydroxyprosta-5,13-dienoic acid
EINECS	Contact for details

Quality Control

Our Prostaglandin G2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. This product is easily oxidized and light-sensitive; allow it to reach room temperature in the original sealed container before opening to minimize condensation and exposure.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.