Description

Vasopressin, 1-Deamino-4-Val-8-Arg- is a synthetic analogue of the endogenous neurohypophysial hormone arginine vasopressin, specifically engineered to enhance its pharmacological profile. This modification results in a compound with potent and selective V2 receptor agonist activity, making it a critical intermediate and active pharmaceutical ingredient (API) for advanced therapeutic development. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on developing treatments for conditions related to fluid balance and specific endocrine disorders.

Application

• Pharmaceutical API Synthesis: Primary use as a high-purity active pharmaceutical ingredient (API) in the manufacture of specific therapeutic agents.
• Biomedical Research: A key reference standard and tool compound for studying the physiology and pharmacology of vasopressin receptors (V1 and V2).
• Endocrinology Studies: Used in preclinical and clinical research to investigate disorders of water balance, such as diabetes insipidus.
• Peptide Chemistry Development: Serves as a model compound in the development and optimization of peptide synthesis, purification, and analytical methods.
• Diagnostic Agent Formulation: Potential use in the formulation of diagnostic agents for assessing renal concentrating ability.

Basic Information

Item	Detail
Product Name	Vasopressin, 1-Deamino-4-Val-8-Arg-
CAS No.	51980-16-6
Molecular Formula	C46H65N13O12S2
Molecular Weight	1032.2 g/mol
Synonyms	Desmopressin Acetate Impurity; DDAVP Impurity; 1-Deamino-8-D-arginine Vasopressin related compound; 1-Desamino-8-D-Arg-Vasopressin; [1-β-Mercaptopropionic acid, 8-D-arginine] Vasopressin; Deamino-8-D-Arginine Vasopressin; Minirin Impurity; ADH Analogue
EINECS	Contact for details

Quality Control

Our Vasopressin, 1-Deamino-4-Val-8-Arg- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical research and development. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature or as specified on the label or CoA. Due to its hygroscopic nature, the container must be kept in a dry environment. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (Mass Spectrometry)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.