Description

p-[[4,4,5,5,5-Pentafluoro-3-(Pentafluoroethyl)-1,2,3-Tris(Trifluoromethyl)Pent-1-Enyl]Oxy]Benzenesulphonyl Chloride is a highly fluorinated, specialized organic intermediate featuring a reactive sulfonyl chloride group. This compound is valued for its unique ability to introduce a perfluoroalkyl ether-substituted benzenesulfonyl moiety, which imparts exceptional chemical stability, hydrophobicity, and specific electronic properties to target molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel fluorinated compounds with tailored performance characteristics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel fluorinated active pharmaceutical ingredients (APIs), particularly sulfonamide-based drugs, where the fluorinated side chain can enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in creating advanced fluorinated herbicides, fungicides, and pesticides, leveraging the fluorine atoms to improve weather resistance, biological activity, and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and resins with superior oil/water repellency, chemical resistance, and low surface energy.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated components for liquid crystal displays (LCDs) and electronic materials, where specific dielectric properties and thermal stability are critical.
• Surface Modification Reagent: Acts as a grafting agent to covalently attach fluorinated, sulfonated functional groups to surfaces, altering wettability and adhesion properties for specialized applications.
• Research & Development: A valuable tool in academic and industrial R&D for exploring structure-activity relationships (SAR) and developing new chemical entities with fluorinated architectures.

Basic Information

Product Name	p-[[4,4,5,5,5-Pentafluoro-3-(Pentafluoroethyl)-1,2,3-Tris(Trifluoromethyl)Pent-1-Enyl]Oxy]Benzenesulphonyl Chloride
CAS No.	51947-19-4
Molecular Formula	C16H4ClF18O3S
Molecular Weight	662.68 g/mol
Synonyms	4-[[4,4,5,5,5-Pentafluoro-3-(pentafluoroethyl)-1,2,3-tris(trifluoromethyl)pent-1-en-1-yl]oxy]benzenesulfonyl chloride; Benzenesulfonyl chloride, 4-[[4,4,5,5,5-pentafluoro-3-(pentafluoroethyl)-1,2,3-tris(trifluoromethyl)-1-penten-1-yl]oxy]-; Perfluoroalkyl ether benzenesulfonyl chloride; Fluorinated sulfonyl chloride intermediate; HFE-7500 sulfonyl chloride derivative (related); 1-(Perfluoro-3-methylbutyl)-2-(perfluoroethyl)-1,2,2-tris(trifluoromethyl)vinyl 4-sulfonylchloridobenzene ether
EINECS	Contact for details

Quality Control

Our production of p-[[4,4,5,5,5-Pentafluoro-3-(Pentafluoroethyl)-1,2,3-Tris(Trifluoromethyl)Pent-1-Enyl]Oxy]Benzenesulphonyl Chloride adheres to stringent in-process controls and final batch analysis to ensure high purity and consistent performance. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.