Description

Elastatinal CAS NO 51798-45-9 is a potent and specific inhibitor of elastase, a proteolytic enzyme. This compound matters significantly in biochemical and pharmacological research for its ability to modulate elastase activity, which is implicated in various inflammatory and tissue degradation processes. It is primarily needed by researchers in life sciences, pharmaceutical development, and biotechnology for studying protease function, developing therapeutic agents, and exploring disease mechanisms related to conditions like emphysema and atherosclerosis.

Application

• Biochemical Research: Used as a specific inhibitor to study the kinetics, function, and inhibition mechanisms of elastase enzymes in vitro.
• Pharmaceutical Development: Serves as a key reference standard and lead compound in the discovery and development of novel anti-inflammatory and anti-protease therapeutics.
• Disease Mechanism Studies: Employed in research models to investigate the role of elastase in pathological conditions such as pulmonary emphysema, chronic obstructive pulmonary disease (COPD), and rheumatoid arthritis.
• Cell Culture & Proteomics: Utilized in cell-based assays and proteomic studies to selectively inhibit elastase activity, helping to elucidate specific signaling pathways and protein interactions.
• Enzyme Characterization: Acts as a critical tool for characterizing the specificity and activity of different elastase isoforms from various biological sources.

Basic Information

Product Name	Elastatinal
CAS No.	51798-45-9
Molecular Formula	C₂₁H₃₉N₅O₆
Molecular Weight	457.57 g/mol
Synonyms	Elastatinal; N-[(S)-1-Carboxy-3-phenylpropyl]-L-alanyl-L-proline; (2S)-1-[(2S)-2-[[(2S)-1-Carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid; Elastase Inhibitor I; N-[(S)-1-Carboxy-3-phenylpropyl]-L-Ala-L-Pro; Ala-Pro Elastase Inhibitor; L-Alanyl-L-prolyl-N-[(1S)-1-carboxy-3-phenylpropyl]amide
EINECS	Contact for details

Quality Control

Our Elastatinal is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets high-purity standards suitable for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Biological Activity (Elastase Inhibition)	IC₅₀ provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.