Description

1-Bromo-4-Fluoro-2,5-Dimethylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its dual functionality, offering reactive sites for both nucleophilic aromatic substitution and cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, serving as a key intermediate in the development of active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated and brominated aromatic core for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and bromine substituents can modulate biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Buchwald-Hartwig amination, enabling the construction of complex biaryl and heteroaryl systems.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities for screening.

Basic Information

Product Name	1-Bromo-4-Fluoro-2,5-Dimethylbenzene
CAS No.	51760-04-4
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	4-Bromo-2,5-dimethylfluorobenzene; 2,5-Dimethyl-4-fluorobromobenzene; 1-Fluoro-4-bromo-2,5-dimethylbenzene; 4-Fluoro-2,5-dimethylbromobenzene; 2-Bromo-5-fluoro-1,4-dimethylbenzene; 4-Bromo-1-fluoro-2,5-dimethylbenzene; 2,5-Dimethyl-1-bromo-4-fluorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Fluoro-2,5-Dimethylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.