Description

16-Phenoxy Tetranor Prostaglandin F2α Methyl Ester is a synthetic prostaglandin analog, a key intermediate in the synthesis of advanced pharmaceutical compounds. Its value lies in its precise chemical structure, enabling the development of targeted therapeutic agents. This high-purity intermediate is essential for research and manufacturing in the pharmaceutical industry, particularly for developing ophthalmic and dermatological treatments.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Development: Used in research and production of medications for glaucoma and ocular hypertension.
• Dermatological Research: Serves as a precursor in studies for hair growth treatments and other dermatological applications.
• Biochemical Research: A valuable tool for studying prostaglandin receptor activity and signal transduction pathways.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for prostaglandin analogs.
• Reference Standard: Used as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	16-Phenoxy Tetranor Prostaglandin F2α Methyl Ester
CAS No.	51638-90-5
Molecular Formula	C27H40O5
Molecular Weight	444.61 g/mol
Synonyms	16-Phenoxy Tetranor PGF2α Methyl Ester; Methyl 16-Phenoxy Tetranor Prostaglandin F2α; 16-Phenoxy Tetranor PGF2α Me Ester; Latanoprost Intermediate; 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenoxypentyl]cyclopentyl]-5-heptenoic Acid Methyl Ester; 16-Phenoxy Tetranor Prostaglandin F2α Me Ester; Prostaglandin F2α 16-Phenoxy Tetranor Methyl Ester; 16-Phenoxy-17,18,19,20-tetranor Prostaglandin F2α Methyl Ester
EINECS	Contact for details

Quality Control

Our 16-Phenoxy Tetranor Prostaglandin F2α Methyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality control protocols are designed to meet the stringent requirements of the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This compound is easily oxidized; for long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) to maintain stability. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.