Description

Phosphoglycolohydroxamate is a specialized biochemical compound with significant research and development applications. This molecule is valued for its role as a potent and specific inhibitor of certain metabolic enzymes, making it a critical tool for mechanistic studies in biochemistry and enzymology. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in metabolic pathway analysis, drug discovery, and the development of novel therapeutic agents.

Application

• Enzyme Inhibition Studies: Used as a specific inhibitor to study the structure and function of key enzymes like enolase and other glycolytic pathway enzymes.
• Pharmaceutical Research: Serves as a lead compound or a biochemical tool in drug discovery programs targeting metabolic diseases and cancer.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening assays for enzyme activity.
• Academic Research: A key reagent in university and institutional labs for fundamental research in cellular metabolism and bioenergetics.
• Diagnostic Reagent Manufacturing: Potential use as a component in specialized diagnostic kits for measuring specific enzyme activities in clinical samples.

Basic Information

Item	Detail
Product Name	Phosphoglycolohydroxamate
CAS No.	51528-59-7
Molecular Formula	C2H6NO7P
Molecular Weight	187.05 g/mol
Synonyms	Phosphoglycolohydroxamic Acid; (2-Hydroxy-2-oxo-1-phosphonoethyl)hydroxylamine; PGHA; N-Hydroxy-2-phosphonoacetamide; 2-Amino-2-oxoethyl dihydrogen phosphate, N-hydroxy-; Enolase Inhibitor; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Phosphoglycolohydroxamate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.