Description

2-Methoxy-1-Ethanesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation or methoxyethylsulfonylation reagent, enabling the introduction of the functionalized sulfonyl group into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs), novel crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent for synthesizing sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process R&D for introducing the 2-methoxyethanesulfonyl moiety.
• Material Science: Potential monomer or modifying agent for creating polymers with specific sulfonyl-based functionalities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates.

Basic Information

Product Name	2-Methoxy-1-Ethanesulfonyl Chloride
CAS No.	51517-01-2
Molecular Formula	C3H7ClO3S
Molecular Weight	158.60 g/mol
Synonyms	2-Methoxyethanesulfonyl chloride; 2-Methoxyethane-1-sulfonyl chloride; 1-Chlorosulfonyl-2-methoxyethane; β-Methoxyethanesulfonyl chloride; Methoxyethylsulfonyl chloride; 2-Methoxyethyl sulfonyl chloride; (2-Methoxyethyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methoxy-1-Ethanesulfonyl Chloride is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.