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5-Bromo-2-Fluorotoluene CAS NO 51437-00-4


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CAS No.:51437-00-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Bromo-2-Fluorotoluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents on a toluene backbone, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated and brominated aromatic motifs.
  • Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and metabolic stability.
  • Liquid Crystal & OLED Materials: Serves as a building block for fluorinated compounds used in electronic display technologies and organic light-emitting diodes.
  • Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution due to the reactivity of the bromine atom.
  • Chemical Research & Development: Utilized in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.
  • Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized halogenated dyes and functional pigments.

Basic Information

Product Name 5-Bromo-2-Fluorotoluene
CAS No. 51437-00-4
Molecular Formula C7H6BrF
Molecular Weight 189.03 g/mol
Synonyms 2-Fluoro-5-bromotoluene; 1-Bromo-4-fluoro-2-methylbenzene; 5-Bromo-2-fluorotoluene; 2-Methyl-4-bromofluorobenzene; 4-Bromo-2-fluorotoluene; Toluene, 5-bromo-2-fluoro-; 2-Fluoro-5-methylbromobenzene
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Quality Control

Our 5-Bromo-2-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from strong bases and incompatible materials. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item Specification
Appearance Colorless to pale yellow clear liquid
Identification (IR) Conforms to structure
Purity (GC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Related Substances (HPLC) Individual impurity ≤ 1.0%
Density ~1.5 g/cm³
Boiling Point ~200-205 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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