Description

4-Bromo-2-Fluorotoluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents on a toluene backbone, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic rings.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the bromine atom offers a site for further functionalization.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials due to its stable aromatic core and halogen handles.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis & Chemical Research: A valuable reagent for introducing fluorinated toluene units into more complex molecular architectures in academic and industrial R&D.

Basic Information

Product Name	4-Bromo-2-Fluorotoluene
CAS No.	51436-99-8
Molecular Formula	C7H6BrF
Molecular Weight	189.03 g/mol
Synonyms	2-Fluoro-4-bromotoluene; 1-Bromo-4-fluoro-2-methylbenzene; 4-Bromo-2-fluoro-1-methylbenzene; Toluene, 4-bromo-2-fluoro-; 2-Methyl-5-bromofluorobenzene; 5-Bromo-2-fluorotoluene; 2-Fluoro-4-methylbromobenzene; 4-Bromo-o-fluorotoluene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.5%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.55 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.