Description

(5Z,13E,15S)-11α,15-Dihydroxyprosta-5,13-Diene-1-Oic Acid is a high-purity prostaglandin derivative, a key intermediate in the synthesis of advanced pharmaceutical compounds. This compound is critical for research and development in medicinal chemistry, particularly for its role as a precursor in the production of prostaglandin analogs. It is primarily utilized by pharmaceutical manufacturers, biotechnology research institutions, and fine chemical synthesis laboratories.

Application

• Pharmaceutical Intermediate: A vital building block for the synthesis of prostaglandin-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and a key reagent in studies of prostaglandin receptors, signaling pathways, and inflammatory responses.
• Medicinal Chemistry: Serves as a core scaffold for the development of novel therapeutic agents targeting a range of conditions.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex, biologically active molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials and commercial drugs.

Basic Information

Product Name	(5Z,13E,15S)-11α,15-Dihydroxyprosta-5,13-Diene-1-Oic Acid
CAS No.	51424-50-1
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	11α,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; 11α,15-Dihydroxyprosta-5,13-dien-1-oic acid; Prostaglandin H2 (PGH2) derivative; 5Z,13E,15S-Prostaglandin intermediate; 11-Deoxyprostaglandin E1 analog; 9-Keto-11α,15-dihydroxyprosta-5,13-dien-1-oic acid
EINECS	Contact for details

Quality Control

Our (5Z,13E,15S)-11α,15-Dihydroxyprosta-5,13-Diene-1-Oic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.