Description

α-Cyclodextrin Hydrate is a cyclic oligosaccharide derived from starch, consisting of six glucose units linked by α-1,4 glycosidic bonds. This unique molecular structure creates a hydrophobic cavity, enabling it to form inclusion complexes with a wide range of guest molecules, thereby enhancing their solubility, stability, and bioavailability. It is an essential functional ingredient for industries requiring advanced molecular encapsulation, including pharmaceuticals, food and beverage, cosmetics, and agrochemicals. The product is supplied as a hydrate to ensure handling stability.

Application

• Pharmaceutical Formulations: Used as a complexing agent to improve the aqueous solubility, dissolution rate, and stability of poorly soluble active pharmaceutical ingredients (APIs).
• Food & Beverage Industry: Functions as a flavor carrier, stabilizer for sensitive compounds (e.g., vitamins, fatty acids), and for cholesterol reduction in food products.
• Cosmetics & Personal Care: Employed to encapsulate fragrances, vitamins, and active ingredients, controlling their release and protecting them from degradation.
• Chemical & Analytical Chemistry: Serves as a chiral selector in capillary electrophoresis and HPLC for enantiomer separation, and as a catalyst or stabilizer in organic synthesis.
• Agrochemicals: Enhances the stability and efficacy of pesticides and herbicides by forming protective inclusion complexes.
• Research & Development: A valuable tool in supramolecular chemistry for studying host-guest interactions and developing novel delivery systems.

Basic Information

Product Name	α-Cyclodextrin Hydrate
CAS No.	51211-51-9
Molecular Formula	C36H60O30 · xH2O
Molecular Weight	972.84 g/mol (anhydrous basis)
Synonyms	α-Cyclodextrin Hydrate; Cyclohexaamylose; α-CD; α-CD; Schardinger's α-dextrin; Cyclomaltohexaose; ACD; CAS 10016-20-3 (anhydrous)
EINECS	233-007-4 (anhydrous)

Quality Control

Our α-Cyclodextrin Hydrate is manufactured under a strict quality management system. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and food-grade applications. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, water content, residue on ignition, and microbiological quality. The product can be supplied to meet various pharmacopoeial specifications (e.g., USP, EP, JP) or Food Chemicals Codex (FCC) standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect flow properties and stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (Karl Fischer)	10.0% - 13.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	+147° to +152°
Heavy Metals	≤ 10 ppm
Microbiological Quality	Meets standard limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.