Description

2,6-Di-o-Methyl-β-Cyclodextrin is a chemically modified derivative of β-cyclodextrin, featuring selective methylation at the 2 and 6 positions of the glucose units. This modification significantly enhances its solubility in water and organic solvents compared to the parent compound, making it an exceptionally versatile molecular encapsulation agent. It is primarily utilized in the pharmaceutical, agrochemical, and specialty chemical industries to improve the solubility, stability, and bioavailability of active ingredients. Its unique cavity structure allows for the formation of stable inclusion complexes with a wide range of guest molecules.

Application

• Pharmaceutical Formulations: Used as a solubility enhancer and stabilizer for poorly water-soluble drugs, improving their bioavailability and dissolution rates.
• Agrochemicals: Employed to enhance the solubility and environmental stability of pesticides and herbicides, leading to more effective and controlled delivery.
• Catalysis & Chemical Synthesis: Acts as a supramolecular catalyst or a reaction medium modifier in organic synthesis, offering selectivity and improving yields.
• Food & Flavor Industry: Utilized to encapsulate and protect sensitive flavors, fragrances, and nutrients from oxidation, light, or heat degradation.
• Analytical Chemistry: Serves as a chiral selector in capillary electrophoresis and HPLC for the separation and analysis of enantiomers.
• Cosmetics & Personal Care: Incorporated into formulations to stabilize active ingredients, control odor, and enhance the delivery of vitamins or other compounds.
• Material Science: Used in the development of functional materials, sensors, and nano-carriers due to its host-guest complexation properties.

Basic Information

Product Name	2,6-Di-o-Methyl-β-Cyclodextrin
CAS No.	51166-71-3
Molecular Formula	C56H98O35
Molecular Weight	1331.38 g/mol
Synonyms	2,6-Dimethyl-β-cyclodextrin; Heptakis(2,6-di-O-methyl)-β-cyclodextrin; DIMEB; 2,6-Di-O-methyl-β-cyclodextrin; 2,6-Di-O-methylcyclomaltoheptaose; 2,6-Di-O-methyl-β-CD; 2,6-DM-β-CD; Methylated β-cyclodextrin (2,6-)
EINECS	Contact for details

Quality Control

Our 2,6-Di-o-Methyl-β-Cyclodextrin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for research and industrial applications. Key parameters such as assay, degree of substitution, and impurity profiles are rigorously controlled. Certificates of Analysis (COA) documenting purity, identity, and specific tests are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed to prevent absorption of atmospheric moisture, which can affect product quality and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details
Degree of Substitution (DS)	~12-14 (Theoretical: 14)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.