Description

Phenylacetic Acid, [1-14C] is a carbon-14 labeled isotopologue of phenylacetic acid, a key aromatic carboxylic acid. This radiolabeled compound is essential for conducting precise metabolic, pharmacokinetic, and environmental fate studies, providing critical data on molecular pathways and degradation. It is primarily utilized by researchers and scientists in the pharmaceutical, agrochemical, and life science sectors for advanced tracer applications and analytical method development.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to study the biotransformation and metabolic fate of phenylacetic acid and related compounds in biological systems.
• Pharmaceutical Research & Development: Critical for ADME (Absorption, Distribution, Metabolism, Excretion) studies of drug candidates that incorporate the phenylacetic acid moiety.
• Agrochemical Science: Employed in environmental fate studies to track the degradation, persistence, and mobility of phenylacetic acid-based pesticides or herbicides.
• Biochemical Synthesis Studies: Serves as a labeled precursor in the research of biosynthetic pathways for various natural products and fine chemicals.
• Analytical Method Development: Used as an internal standard or reference material in advanced chromatographic (e.g., LC-MS) and spectroscopic analytical techniques.
• Microbial Metabolism Research: Applied in studies investigating the microbial degradation of aromatic compounds in environmental and industrial contexts.

Basic Information

Product Name	Phenylacetic Acid, [1-14C]
CAS No.	51146-16-8
Molecular Formula	C8H814CO2H
Molecular Weight	~138.14 (based on 12C form)
Synonyms	2-Phenyl[1-14C]acetic Acid; Benzeneacetic-1-14C Acid; α-Toluic-1-14C Acid; (1-14C)Phenylacetic Acid; PAA-1-14C; ω-Phenyl[1-14C]acetic Acid; Carbon-14 Labeled Phenylacetic Acid; Radiolabeled Phenylacetic Acid
EINECS	Contact for details

Quality Control

Every batch of Phenylacetic Acid, [1-14C] is manufactured and analyzed under strict quality protocols to ensure high chemical, radiochemical, and isotopic purity. Our quality assurance includes verification of specific activity and rigorous testing for radiochemical impurities. A comprehensive Certificate of Analysis (COA) detailing purity, specific activity (mCi/mmol or GBq/mmol), and analytical methods (e.g., HPLC, radio-HPLC) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended cold temperatures (e.g., -20°C or as specified on the label) to maintain stability and specific activity. Store in accordance with all local and national regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 98% (Chemical Purity)
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Solvent (if supplied as solution)	Specified on COA (e.g., Ethanol, Toluene)
Concentration (if supplied as solution)	Specified on COA (e.g., 1.0 mCi/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.