Description

(2-Cyanophenyl)Methanesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the methanesulfonyl (mesyl) group into target molecules, which is essential for modifying physicochemical properties and biological activity. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the sulfonyl moiety enhances efficacy and stability.
• Material Science Research: Employed in the creation of specialized polymers and functional materials that require sulfonated aromatic structures.
• Chemical Biology Probes: Utilized to develop activity-based probes and labeling reagents for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(2-Cyanophenyl)Methanesulfonyl Chloride
CAS No.	51045-34-2
Molecular Formula	C8H6ClNO2S
Molecular Weight	215.66 g/mol
Synonyms	2-Cyanobenzylsulfonyl Chloride; (2-Cyanobenzyl)sulfonyl Chloride; Methanesulfonyl chloride, (2-cyanophenyl)-; o-Cyanobenzylsulfonyl Chloride; 2-(Chlorosulfonylmethyl)benzonitrile; α-Toluenesulfonyl chloride, α-cyano-; Benzonitrile, 2-[(chlorosulfonyl)methyl]-
EINECS	Contact for details

Quality Control

Every batch of (2-Cyanophenyl)Methanesulfonyl Chloride is manufactured and tested under strict quality management systems to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.