Description

Demethylcephalotaxinone is a high-purity, specialized alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate and reference standard for the development of novel bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex natural products and potential therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for cephalotaxine-type alkaloids and related analogs with potential biological activity.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and compound identification via HPLC, LC-MS, or NMR.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize the pharmacological profiles of new chemical entities.
• Academic & Institutional Research: Serves as a substrate or reagent in studies focused on organic synthesis methodologies, natural product chemistry, and biochemical mechanisms.
• Fine Chemical Synthesis: Utilized as a precursor for the custom synthesis of more complex, value-added specialty chemicals for various research applications.

Basic Information

Product Name	Demethylcephalotaxinone
CAS No.	51020-45-2
Molecular Formula	C17H19NO5
Molecular Weight	317.34 g/mol
Synonyms	(-)-Demethylcephalotaxinone; 3-Desmethylcephalotaxinone; Cephalotaxinone, 3-demethyl-; (1S,3aR,14bS)-1,2,3,3a,4,5,7,14b-Octahydro-1-hydroxy-6-methoxy-3-oxo-1H,12H-benzo[a]pyrrolo[3,4-c]phenanthridin-12-one; 1-Hydroxy-6-methoxy-3-oxo-1,2,3,3a,4,5,7,14b-octahydro-1H,12H-benzo[a]pyrrolo[3,4-c]phenanthridin-12-one
EINECS	Contact for details

Quality Control

Our Demethylcephalotaxinone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is thoroughly characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.