Description

Proparathormone CAS NO 50815-54-8 is a synthetic peptide analog of parathyroid hormone, a key regulator of calcium and phosphate homeostasis. This high-purity compound is critical for advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in metabolic bone disease studies, endocrine research, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of calcium metabolism, bone remodeling, and parathyroid hormone receptor (PTH1R) signaling pathways.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the R&D of treatments for osteoporosis, hypoparathyroidism, and other bone mineral disorders.
• Diagnostic Reagent Manufacturing: Employed in the production of immunoassay kits and other in vitro diagnostic tools for measuring parathyroid hormone levels.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate the effects of PTH on osteoblast and osteoclast activity.
• Academic Research: A vital tool for universities and laboratories exploring endocrinology, peptide hormone action, and molecular biology.

Basic Information

Product Name	Proparathormone
CAS No.	50815-54-8
Molecular Formula	C₁₈₁H₂₉₁N₅₅O₅₁S₂
Molecular Weight	4117.8 g/mol (approx.)
Synonyms	Parathyroid Hormone (1-34), human; Teriparatide; PTH (1-34); hPTH(1-34); Recombinant human parathyroid hormone (1-34); Parathormone fragment 1-34; FORTEO® (brand name); LY333334
EINECS	Contact for details

Quality Control

Our Proparathormone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, peptide mapping, and mass spectrometry for identity confirmation, to ensure it meets high-grade research and development standards. Certificates of Analysis (COA) detailing purity, potency, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Assay (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Determined by in vitro assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.