Description

3-Iodobenzenesulfonyl Chloride is a versatile and reactive organoiodine building block primarily used in organic synthesis. Its value lies in the sulfonyl chloride functional group, which readily undergoes nucleophilic substitution, making it a key intermediate for constructing sulfonamides and sulfonate esters. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is employed in the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the sulfonyl moiety confers biological activity.
• Material Science Research: Serves as a building block for creating functional polymers, dyes, and liquid crystals with specific electronic or optical properties.
• Chemical Biology & Proteomics: Utilized as a reagent for protein labeling, activity-based probes, and the study of enzyme mechanisms due to its electrophilic character.
• Cross-Coupling Reactions: The iodine atom can participate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) for further structural diversification.
• Sulfonylation Agent: Acts as an efficient sulfonylation agent for alcohols, amines, and other nucleophiles in laboratory and process-scale chemistry.

Basic Information

Product Name	3-Iodobenzenesulfonyl Chloride
CAS No.	50702-38-0
Molecular Formula	C6H4ClIO2S
Molecular Weight	302.52 g/mol
Synonyms	m-Iodobenzenesulfonyl Chloride; 3-Iodophenylsulfonyl Chloride; Benzenesulfonyl chloride, 3-iodo-; 1-Iodo-3-(chlorosulfonyl)benzene; 3-Iodobenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Iodobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.