Description

5-Bromo-Naphthalene-1-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a versatile sulfonylation reagent, enabling the introduction of the naphthalene sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with specific activity profiles.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and functional materials.
• Dye & Pigment Manufacturing: Employed in the synthesis of complex organic dyes and pigments due to the naphthalene backbone.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying biomolecules in research applications.
• Ligand & Catalyst Development: Used to create sophisticated ligands for metal complexes and organocatalysts.

Basic Information

Product Name	5-Bromo-Naphthalene-1-Sulfonyl Chloride
CAS No.	50638-04-5
Molecular Formula	C10H6BrClO2S
Molecular Weight	305.57 g/mol
Synonyms	1-Bromo-5-naphthalenesulfonyl chloride; 5-Bromo-1-naphthalenesulfonyl chloride; 1-Naphthalenesulfonyl chloride, 5-bromo-; 5-Bromonaphthalene-1-sulfonyl chloride; NSC 403103; 5-Br-1-NsCl
EINECS	Contact for details

Quality Control

Our 5-Bromo-Naphthalene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.