Description

1-(2,2,2-Trifluoroethyl)-3-(Trifluoromethyl)Benzene is a high-purity fluorinated aromatic compound, valued for its unique chemical structure that imparts significant lipophilicity and metabolic stability. This compound serves as a critical advanced intermediate in the synthesis of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is essential for research and development teams focused on creating novel active ingredients, including pharmaceuticals, crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting the central nervous system (CNS) and other therapeutic areas requiring fluorinated motifs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl and trifluoroethyl groups enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
• Organic Synthesis & Catalysis: Employed as a specialty reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis due to its electron-withdrawing properties.
• Polymer & Material Science: Incorporated into high-performance polymers and coatings to impart chemical resistance, low surface energy, and thermal stability.

Basic Information

Item	Details
Product Name	1-(2,2,2-Trifluoroethyl)-3-(Trifluoromethyl)Benzene
CAS No.	50562-22-6
Molecular Formula	C9H6F6
Molecular Weight	228.14 g/mol
Synonyms	3-(Trifluoromethyl)benzyl trifluoride; α,α,α-Trifluoro-3-(trifluoromethyl)toluene; 1-(Trifluoroethyl)-3-(trifluoromethyl)benzene; m-(Trifluoromethyl)benzotrifluoride; 3-Trifluoromethylbenzyl trifluoride; (3-(Trifluoromethyl)phenyl)trifluoroethane; Benzene, 1-(2,2,2-trifluoroethyl)-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1-(2,2,2-Trifluoroethyl)-3-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and sources of ignition. Due to its fluoride/strong alkali chemical property, ensure it is segregated from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (20°C)	~1.4 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.