Description

1-Fluoro-4-(2,2,2-trifluoroethyl)benzene is a high-purity fluorinated aromatic building block of significant commercial interest. This compound is valued for its unique trifluoroethyl side chain, which imparts desirable electronic and lipophilic properties to advanced molecular structures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for use in synthesis and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorine atoms for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides where the fluorine moiety enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes.
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine into polymers, improving chemical resistance and surface properties.
• Organic Synthesis & Catalysis Research: A versatile reagent in academic and industrial R&D for constructing complex fluorinated aromatic systems.
• Fluorine-19 NMR Spectroscopy: Can be utilized as a reference standard or probe in analytical chemistry due to its distinct fluorine signature.

Basic Information

Product Name	1-Fluoro-4-(2,2,2-trifluoroethyl)benzene
CAS No.	50561-99-4
Molecular Formula	C8H6F4
Molecular Weight	178.13 g/mol
Synonyms	4-(2,2,2-Trifluoroethyl)fluorobenzene; p-(Trifluoroethyl)fluorobenzene; 1-Fluoro-4-(trifluoroethyl)benzene; α,α,α-Trifluoro-p-fluoroethylbenzene; 4-Fluoro-α,α,α-trifluoroethylbenzene; (4-Fluorophenyl)trifluoroethane; Benzene, 1-fluoro-4-(2,2,2-trifluoroethyl)-
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-(2,2,2-trifluoroethyl)benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.3 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.