Description

2-Formyl-5-Nitrobenzotrifluoride, 4-Nitro-Alpha,Alpha,α-Trifluoro-o-Tolualdehyde is a high-value aromatic trifluoromethylated intermediate with a strategically positioned formyl and nitro group. This compound matters for its role as a versatile building block in the synthesis of complex, fluorinated molecules, which are critical for developing advanced materials and pharmaceuticals. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries seeking to incorporate the unique properties of the trifluoromethyl group into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, anti-inflammatory agents, and anti-infectives where the trifluoromethyl group enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the nitro and formyl groups allow for further functionalization to create molecules with specific modes of action.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalysis, particularly in cross-coupling reactions important for fine chemical manufacturing.
• Material Science Research: Employed in the creation of fluorinated organic compounds for advanced materials, such as liquid crystals, polymers, and organic electronic components, where fluorine atoms can modify electronic properties and stability.
• Dye and Pigment Intermediate: The reactive formyl and nitro groups make it suitable for constructing complex chromophores used in high-performance dyes and pigments.

Basic Information

Item	Detail
Product Name	2-Formyl-5-Nitrobenzotrifluoride, 4-Nitro-Alpha,Alpha,α-Trifluoro-o-Tolualdehyde
CAS No.	50551-17-2
Molecular Formula	C8H4F3NO3
Molecular Weight	219.12 g/mol
Synonyms	4-Nitro-2-(trifluoromethyl)benzaldehyde; 2-Formyl-5-nitrobenzotrifluoride; 5-Nitro-2-(trifluoromethyl)benzaldehyde; 2-(Trifluoromethyl)-4-nitrobenzaldehyde; 4-Nitro-α,α,α-trifluoro-o-tolualdehyde; 4-Nitro-2-trifluoromethylbenzaldehyde; o-Tolualdehyde, 4-nitro-α,α,α-trifluoro-; 2-Trifluoromethyl-4-nitrobenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Formyl-5-Nitrobenzotrifluoride undergoes rigorous quality testing to ensure compliance with industry standards for high-purity intermediates. Our quality assurance includes identity confirmation, purity analysis, and impurity profiling using advanced analytical techniques. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.