Description

Anthranilic Acid, [Carboxyl-14C] is a carbon-14 labeled derivative of anthranilic acid (2-aminobenzoic acid), where the radioactive isotope is specifically incorporated at the carboxyl carbon position. This labeled compound is an essential tool for metabolic, pharmacokinetic, and environmental fate studies, enabling precise tracking and quantification of the parent molecule and its derivatives. It is primarily utilized by researchers and scientists in the pharmaceutical, agrochemical, and life science industries for advanced tracer applications and analytical method development.

Application

• Tracer Studies in Drug Metabolism & Pharmacokinetics (DMPK): Used to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of pharmaceutical compounds derived from or related to anthranilic acid.
• Agrochemical Research: Employed in environmental fate studies to track the degradation pathways, soil metabolism, and plant uptake of agrochemicals containing the anthranilate moiety.
• Biochemical Pathway Analysis: Serves as a labeled precursor or intermediate for studying biosynthetic pathways, such as tryptophan metabolism or the synthesis of bioactive alkaloids.
• Analytical Method Development: Acts as an internal standard or reference material in Liquid Chromatography-Mass Spectrometry (LC-MS) and other chromatographic techniques for quantitative analysis.
• Material Science Research: Used in the development and study of labeled polymers, dyes, or corrosion inhibitors where the anthranilic acid structure is incorporated.

Basic Information

Product Name	Anthranilic Acid, [Carboxyl-14C]
CAS No.	5848-20-4
Molecular Formula	C7H714CNO2
Molecular Weight	~138.1 g/mol (exact mass depends on 14C enrichment)
Synonyms	2-Aminobenzoic-14C(carboxyl) acid; [Carboxy-14C]Anthranilic Acid; o-Aminobenzoic-14C(carboxyl) acid; Vitamin L1 (labeled); 1-Amino-2-carboxybenzene-14C(carboxyl); Benzamic acid-14C(carboxyl); 2-Carboxyaniline-14C(carboxyl)
EINECS	Contact for details

Quality Control

Every batch of our carbon-14 labeled Anthranilic Acid is produced and analyzed under strict quality systems. We ensure high chemical and radiochemical purity, with comprehensive testing including HPLC for chemical purity and Liquid Scintillation Counting (LSC) for radiochemical concentration and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, specifying batch-specific data on specific activity, purity, and solvent composition. Our manufacturing and handling processes adhere to relevant radioisotope handling and transportation regulations.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storage under inert atmosphere or in a desiccator to maintain stability. Handle and store in accordance with all applicable local, national, and international regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Chemical Purity (HPLC)	≥ 98.0%
Radiochemical Purity (HPLC-LSC)	≥ 97.0%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Solvent (if supplied as solution)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.