Description

Cotinine fumarate is a high-purity salt form of cotinine, a major metabolite of nicotine, offering enhanced stability and handling properties for advanced research and development. This compound is critical for studies in pharmacology, toxicology, and the development of diagnostic assays and smoking cessation aids. It serves as an essential reference standard and intermediate for pharmaceutical, diagnostic, and academic laboratories requiring precise and reliable biochemical tools.

Application

• Pharmaceutical Reference Standard: Used as a primary standard for the quantification and validation of cotinine levels in bioanalytical methods, including LC-MS and ELISA.
• Biochemical Research: Employed in metabolic and pharmacokinetic studies to understand nicotine metabolism, receptor interactions, and biomarker research.
• Diagnostic Kit Manufacturing: A key component in the production of immunoassay kits for the detection of tobacco use and exposure in clinical and forensic settings.
• Smoking Cessation Product Development: Utilized in the research and formulation of next-generation therapeutics and nicotine replacement therapies.
• Toxicology and Safety Testing: Applied in studies assessing the long-term effects and safety profiles of nicotine and its metabolites.

Basic Information

Product Name	Cotinine Fumarate
CAS No.	5695-98-7
Molecular Formula	C₁₀H₁₂N₂O • C₄H₄O₄
Molecular Weight	308.29 g/mol
Synonyms	Cotinine Hydrogen Fumarate; (S)-Cotinine Fumarate; 1-Methyl-5-(3-pyridyl)-2-pyrrolidinone Fumarate; Cotinine Fumarate Salt; Cotinine (S)-Fumarate; Cotinine Monofumarate; Fumaric Acid Cotinine Salt; Cotinine Hemifumarate
EINECS	Contact for details

Quality Control

Our Cotinine fumarate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant pharmacopeial guidelines and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.