Description

2-Methylallylmagnesium Chloride is a highly reactive Grignard reagent, a cornerstone organometallic compound for advanced organic synthesis. Its value lies in its ability to efficiently introduce the versatile 2-methylallyl (prenyl) group into molecular frameworks, enabling the construction of complex intermediates. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise carbon-carbon bond formation for active ingredient development.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing prenylated side chains and complex carbon skeletons found in active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of advanced fungicides, herbicides, and plant growth regulators that incorporate allylic structures.
• Fine Chemical Production: Enables the synthesis of specialty monomers, flavors, fragrances, and advanced material precursors.
• Polymer Chemistry: Serves as an initiator or functionalizing agent for the synthesis of specialty polymers with tailored properties.
• Cross-Coupling Reactions: Acts as a nucleophilic coupling partner in transition metal-catalyzed reactions like Kumada coupling.
• Academic & Industrial R&D: A fundamental tool for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	2-Methylallylmagnesium Chloride
CAS No.	5674-01-1
Molecular Formula	C4H7ClMg
Molecular Weight	114.85 g/mol
Synonyms	2-Methylallylmagnesium Chloride; (2-Methyl-2-propenyl)magnesium Chloride; Prenylmagnesium Chloride; 2-Methylallyl Grignard Reagent; 2-Methyl-2-propen-1-ylmagnesium Chloride; 2-Methylprop-2-en-1-ylmagnesium Chloride; Isobutenylmagnesium Chloride; Magnesium, chloro(2-methyl-2-propenyl)-
EINECS	227-128-7

Quality Control

Our 2-Methylallylmagnesium Chloride is manufactured under stringent process controls to ensure batch-to-batch consistency and high reactivity. Quality is verified through rigorous analytical testing, including titration for Grignard concentration and impurity profiling. A Certificate of Analysis (COA) detailing assay, purity, and solution concentration (typically provided in standard solvents like THF or diethyl ether) is supplied with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile, hygroscopic (moisture-sensitive), and easily oxidized nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. For solutions, maintain at the recommended temperature as specified on the container label, typically between 2°C and 8°C for extended stability. Keep away from heat, sparks, open flames, and incompatible materials such as water, acids, and oxidizing agents.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light yellow
Identification (IR / NMR)	Conforms to structure
Assay (Titration)	0.5 M to 2.0 M in specified solvent (e.g., THF)
Purity (GC / HPLC)	≥ 95% (on an anhydrous basis)
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.